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Chemistry

How an ancient alchemy technique is transforming modern chemistry

Today’s chemistry is a wet business, mostly done by mixing compounds in liquid solvents. But a push towards using dry powders instead is proving surprisingly effective

By Hayley Bennett

20 May 2025

New Scientist. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

Mechanochemistry involves smashing and grinding powders together

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Imagine yourself in a chemistry lab. You are probably picturing a scene featuring a whole load of liquids – fluids bubbling in round-bottomed flasks, solutions swirling in test tubes, droplets running down condensers. It is a cliché, but one that accurately describes what these spaces have looked like for centuries the world over.

There isn’t much frothing or bubbling going on in Tomislav Friščić’s lab, though. That’s because he and his team at the University of Birmingham, UK, are trying to do away with liquid chemistry. The tools of their trade…

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